Correlation between IL-6 levels and polymerized human serum albumin ceptor (PHSAR) in serum of chronic hepatitis patients / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 33-36, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-355132
ABSTRACT
<p><b>BACKGROUND</b>To investigate the relationship between interleukin-6 (IL-6) levels in serum and HBV replication and the role of IL-6 in liver damage in chronic hepatitis B patients.</p><p><b>METHODS</b>Detected IL-6 levels and polymerized human serum albumin receptor (PHSA-R) in serum of different type of HBV markers positive patients and of different degree of chronic hepatitis B patients.</p><p><b>RESULTS</b>The results showed that the serum IL-6 levels were increased significantly in PHSA-R positive patients than in PHSA-R negative patients in chronic hepatitis B (P<0.01). The serum IL-6 levels were correlated with the levels of PHSA-R (r=0.694, P<0.01), and the degree of symptoms.</p><p><b>CONCLUSIONS</b>This study suggested that the IL-6 levels in serum of hepatitis B patients correlated HBV replication and the degree of liver damage, serum IL-6 levels may be used as a value indicating of HBV replication, the degree of symptoms and the effect of treatment.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Virus Replication
/
Blood
/
Hepatitis B virus
/
Interleukin-6
/
Receptors, Albumin
/
Hepatitis B, Chronic
Limits:
Adult
/
Aged
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS