Hearing screening in infants with congenital cytomegalovirus infection / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 358-360, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-355206
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the impact of congenital cytomegalovirus infection on the hearing ability in infants.</p><p><b>METHODS</b>By using the tools of distortion product otoacoustic emission (DPOAE) and auditory brain-stem response (ABR), the hearing ability of 38 infants with congenital cytomegalovirus infection and 16 cases of normal controls during neonatal periods was screened with a follow-up study at 6 and 24 months.</p><p><b>RESULT</b>In infants with congenital cytomegalovirus infection, 86.8% (66/76) ears at neonatal stage and 76.3% (58/76) ears at 6 months passed the tests; while in normal controls, 96.9% (31/32) ears passed the tests. The reaction threshold of ABR V in infants with congenital cytomegalovirus infection was higher than that in normal controls (P<0.005). Furthermore,in infants with congenital cytomegalovirus infection, 13 ears (17.1%) were extreme hearing loss, 5 ears (6.6%) were severe hearing loss, and 6 ears (7.9%) were moderately severe hearing loss. The incidence of hearing loss during the follow-up was 7.9% (3/38) at neonatal stage, 23.7% (9/38) at 3-4 months, and 7.9% (3/38) after 6 months.</p><p><b>CONCLUSION</b>The congenital cytomegalovirus infection could cause the prompt and late-onset hearing loss. The combination of the laboratory evidence with the dynamic hearing screening may contribute to the early detection of hearing loss in infants with congenital cytomegalovirus infection.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
China
/
Epidemiology
/
Follow-Up Studies
/
Evoked Potentials, Auditory, Brain Stem
/
Neonatal Screening
/
Otoacoustic Emissions, Spontaneous
/
Cytomegalovirus Infections
/
Hearing Loss, Bilateral
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Screening study
Limits:
Female
/
Humans
/
Male
/
Infant, Newborn
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2005
Type:
Article
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