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Omics of vector mosquitoes: a big data platform for vector biology and vector-borne diseases / 南方医科大学学报
Journal of Southern Medical University ; (12): 625-630, 2015.
Article in Chinese | WPRIM | ID: wpr-355313
ABSTRACT
Recently the studies on mosquito genomics, transcriptomics and small RNAomics developed rapidly with the novel biotechnologies of the next generation sequencing techniques. The genome sequences of several important vector mosquitoes including Anopheles gambiae, Culex quinquefasciatus, and Aedes aegypti have been published. The genome sizes vary among the different species of mosquitoes and are consistent with the number of the repeat regions. The released genome sequences facilitate gene cloning and identification as for OBP, OR and dsx genes. Transcriptomics provides a useful tool for functional analyses of the mosquito genes, and using this technique, the molecular basis of mosquito blooding, gland proteins and diapauses have been explored. Studies on small RNAomics suggest important roles of miRNAs and piRNAs in ovary development, blood digestion, and immunity against virus infection. The studies on mosquito omics have generated a big data platform for investigation of vector biology and vector-transmitted disease prevention.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Aedes / Gene Expression Profiling / Culex / Genomics / MicroRNAs / Genome, Insect / High-Throughput Nucleotide Sequencing / Genetics / Anopheles Limits: Animals Language: Chinese Journal: Journal of Southern Medical University Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Aedes / Gene Expression Profiling / Culex / Genomics / MicroRNAs / Genome, Insect / High-Throughput Nucleotide Sequencing / Genetics / Anopheles Limits: Animals Language: Chinese Journal: Journal of Southern Medical University Year: 2015 Type: Article