Improvements of lentiviral vector and its application in gene therapy of hematological diseases / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 208-212, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-355681
ABSTRACT
As lentiviral vector holds the characteristics of higher transfection to non-dividing cells, larger capacity of transfer gene fragments, long-term expression of therapeutic gene and lower rate of immunological response, therefore it becomes potential viral vector in gene therapy. Improvements of lentiviral vector, human immunodeficiency virus type-I as example, and its application in gene transfer for gene therapy of hematological diseases are emphasized in this review.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Hematopoietic Stem Cells
/
Genetic Therapy
/
Leukemia
/
HIV-1
/
Beta-Thalassemia
/
Lentivirus
/
Hematopoietic Stem Cell Transplantation
/
Fanconi Anemia
/
Genetic Vectors
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2003
Type:
Article
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