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Efficacy comparison between drug-eluting stents versus cutting balloon angioplasty followed by bare metal stents for the treatment of ostial lesions of the left anterior descending coronary artery / 中华心血管病杂志
Chinese Journal of Cardiology ; (12): 702-705, 2008.
Article in Chinese | WPRIM | ID: wpr-355909
ABSTRACT
<p><b>OBJECTIVE</b>To compare the short and long-term clinical and angiographic outcomes of drug-eluting stents (DES) versus cutting balloon angioplasty followed by bare metal stents (CBA + BMS) for the treatment of ostial lesions of the left anterior descending coronary artery (LAD).</p><p><b>METHODS</b>A total of 51 consecutive patients with LAD ostial lesions were treated by DES and all patients had completed 2-year clinical follow-up, 50 consecutive patients with LAD ostial lesions treated by CBA + BMS and followed up for 2 years prior to the DES era (May 2000 to November 2003) served as control group.</p><p><b>RESULTS</b>In DES group, one patient experienced acute myocardial infarction (AMI) during hospitalization, the in-hospital major adverse cardiac event (MACE) was 1.96% (1/51), angiography follow-up data at 6-8 months were available in 29 patients and the in-DES restenosis was 10.3% (3/29), at 2-year clinical follow-up, 1 patient died, 4 patients received target lesion revascularization. Total MACE rate was 9.8% (5/51). In CBA + BMS group, there was no in-hospital death and AMI. Angiographic follow-up at 6-8 months was completed in 28 cases and in-stent restenosis rate was 17.9% (5/28). During 2-year follow-up, there was no death and AMI and 6 patients underwent target lesion revascularization. MACE rate was 12% (6/50) in this group.</p><p><b>CONCLUSION</b>This study showed that both clinical and angiographic outcomes were comparable between DES and CBA + BMS treated patients with LAD ostial lesions during the 2-year follow up period.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: General Surgery / Therapeutics / Coronary Artery Disease / Angioplasty, Balloon, Coronary / Stents / Follow-Up Studies / Treatment Outcome / Angioplasty, Balloon / Drug-Eluting Stents Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: Chinese Journal: Chinese Journal of Cardiology Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: General Surgery / Therapeutics / Coronary Artery Disease / Angioplasty, Balloon, Coronary / Stents / Follow-Up Studies / Treatment Outcome / Angioplasty, Balloon / Drug-Eluting Stents Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: Chinese Journal: Chinese Journal of Cardiology Year: 2008 Type: Article