Sesquiterpenoids of Coniogramme maxima / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study sesquiterpenoids of Coniogramme maxima.</p><p><b>METHOD</b>Chemical constituents were separated by chromatography and their structures were identified according to physicochemical property and spectrum data.</p><p><b>RESULT</b>Fifteen compounds were separated by chromatography technique. Their structures were determined by spectral data, including 10 sesquiterpenoids as (3S)-pteroside D (1), epi-pterosin L (2), pterosin D (3), onitin (4), pterosin Z (5), onitisin (6), onitisin-glucopyranoside (7), onitin-15-O-beta-D-glucopyranoside (8), (2S,3R)-pterosin-L-2'-O-beta-D-glucopyranoside (9) and (3R)-peterosin D-3-O-beta-D-glucopyranoside (10). The other compounds were uracil (11), 3,4-dihydroxybenzaldehyde (12), 5-hydroxymethyl-2-furancarboxaldehyde (13), beta-sitosterol (14) and daucosterol (15).</p><p><b>CONCLUSION</b>The above 15 compounds are separated from C. maxima for the first time, including 9 compounds being first separated from genus Coniogramme.</p>