Research advances on drug resistance and anti-apoptosis of leukemic cells associated with bone marrow stromal cells--review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 529-533, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-356520
ABSTRACT
The bone marrow microenvironment composed of bone marrow cell, their secreted cytokines and extra-cellular medium (ECM), plays an important role in the process of hematopoiesis, hematonosis, apoptosis of malignant blood cells. In this review, the mechanisms for the protection of the leukemiic cells from the drug-induced apoptosis by bone marrow stromal cells and the related progress were summarized.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Bone Marrow Cells
/
Leukemia
/
Stromal Cells
/
Apoptosis
/
Drug Resistance, Neoplasm
/
Proto-Oncogene Proteins c-bcl-2
/
Apoptosis Regulatory Proteins
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2005
Type:
Article
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