Advances of study on activation of nuclear factor kappaB in hematological malignancies and its mechanism--review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 518-523, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-356522
ABSTRACT
The nuclear factor kappa B(NF-kappaB) plays a crucial role in inflammatory, immune response, embryo development, cell proliferation and apoptosis, cell cycle control as well as tumorgenesis. In recent years, a variety of investigations have demonstrated that NF-kappaB was closely associated with the pathogenesis of hematological malignancies such as leukemia, lymphoma and multiple myeloma. Nowadays, increasingly attention has been paid to the studies on the activation and its mechanism of NF-kappaB in the hematogenic malignancies. So that, in this article, progress on these aspects is reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
NF-kappa B
/
Hematologic Neoplasms
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2005
Type:
Article
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