Research progress in human enterovirus recombination / 病毒学报
Chinese Journal of Virology
;
(6): 180-187, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-356618
ABSTRACT
Complex genetic variation has been known to occur during the transmission of human enterovirus (HEV), and the HEV virulence and pathogenicity enhanced by genetic recombination also pose a serious threat to human health. In recent years, the interest in recombination mechanism of genetic plasticity has been renewed with the emergence of pathogenic recombinant circulating vaccine-derived polioviruses, which were implicated in poliomyelitis outbreaks in several regions of the world with insufficient vaccination coverage. This paper reviews recent research progress in HEV genome, including evolutionary characteristics, recombination types, and in vitro recombinant construction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recombination, Genetic
/
Viral Proteins
/
Virology
/
Classification
/
Enterovirus
/
Biomedical Research
/
Enterovirus Infections
/
Genetics
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Virology
Year:
2014
Type:
Article
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