Evaluation of left ventricular diastolic function by TE-e' measurement using dual Doppler echocardiography in coronary heart disease patients with preserved systolic function / 南方医科大学学报
Journal of Southern Medical University
;
(12): 349-353, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-356923
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the accuracy of the time interval between the onset of early transmitral flow velocity (E) and that of early diastolic mitral annular velocity (e') (TE-e') measured by dual Doppler echocardiography in the diagnosis of diastolic dysfunction.</p><p><b>METHODS</b>Seventy-seven coronary heart disease patients with preserved systolic function underwent a echocardiographic study. Early transmitral flow velocity E and early diastolic mitral annular velocity e' were simultaneously recorded by dual Doppler echocardiography. The E/e' and TE-e' were calculated and compared with the left ventricular end diastolic pressure (LVEDP), which was measured invasively. The validity of TE-e', E/e' and their combination was analyzed in estimating left ventricular dysfunction (LVEDP ≥12 mmHg).</p><p><b>RESULTS</b>The single-beat E/e' and TE-e' were correlated with the LVEDP (r=0.79 and 0.42, respectively, P<0.001). Receiver-operating characteristic analysis showed that the optimal cut-off for TE-e' was 38 ms (sensitivity 54%, specificity 79%, AUC 0.71) and that for E/e' was 9.2 (sensitivity 74%, specificity 81%, AUC 0.87) for diagnosis of left ventricular diastolic dysfunction. The combined cut-offs of TE-e'≥38 ms and E/e'≥9.2 had a sensitivity of 100% and a specificity of 62% in diagnosing left ventricular diastolic dysfunction with an AUC of 0.96.</p><p><b>CONCLUSION</b>In patients with coronary heart disease, the simultaneous recording of TE-e' by dual Doppler echocardiography can accurately estimate diastolic dysfunction, and its combination with E/e' can further improve the diagnostic accuracy.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Diagnostic Imaging
/
Ventricular Dysfunction, Left
/
Echocardiography, Doppler, Pulsed
/
Coronary Disease
Type of study:
Diagnostic study
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2014
Type:
Article
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