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Comparison of endoscopic submucosal tunnel dissection with endoscopic submucosal dissection for large esophageal superficial neoplasms / 南方医科大学学报
Journal of Southern Medical University ; (12): 36-40, 2014.
Article in Chinese | WPRIM | ID: wpr-356991
ABSTRACT
<p><b>OBJECTIVE</b>To compare the safety and efficiency of endoscopic submucosal tunnel dissection (ESTD) and endoscopic submucosal dissection (ESD) for large esophageal superficial neoplasms.</p><p><b>METHODS</b>A total of 235 consecutive patients undergoing endoscopic resection for esophageal neoplasms between October, 2010 and June, 2013 in our endoscopy center were analyzed retrospectively. According to the inclusion and exclusion criteria, 29 patients receiving ESTD or ESD for large esophageal superficial neoplasms were enrolled for data analysis.</p><p><b>RESULTS</b>Of the 29 patients, 11 underwent ESTD and 18 received ESD. The dissection speed of ESTD was significantly higher than that of ESD (22.4∓5.2 mm(2)/min vs 12.2∓4.0 mm(2)/min, P<0.05). Despite a similar en bloc rate between the two groups (100% [11/11] vs 88.9% [16/18], P>0.05), the radical curative rate of ESTD was significantly greater than that of ESD (81.8% [9/11] vs 66.7% [12/18], P<0.05). No serious bleeding or perforation occurred in the patients except for 1 in ESD group with intraoperative bleeding, which was managed with hemostatic forceps. Eight patients had postoperative esophageal strictures in relation with circumferential extension and the longitudinal length (P<0.05).</p><p><b>CONCLUSION</b>ESTD is a safe and effective alternative for large esophageal superficial neoplasms with a shortened operative time, a higher dissection speed and a higher radical curative rate in comparison with ESD, but postoperative esophageal strictures should be closely monitored especially for lesions more than 3/4 of the circumferential extension or exceeding 50 mm.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: General Surgery / Esophageal Neoplasms / Retrospective Studies / Endoscopy / Esophagus / Mucous Membrane Type of study: Observational study Limits: Aged / Female / Humans / Male Language: Chinese Journal: Journal of Southern Medical University Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: General Surgery / Esophageal Neoplasms / Retrospective Studies / Endoscopy / Esophagus / Mucous Membrane Type of study: Observational study Limits: Aged / Female / Humans / Male Language: Chinese Journal: Journal of Southern Medical University Year: 2014 Type: Article