The investigation of bioadhesive property of carbomer 934 by gamma camera in vivo / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 423-425, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-357011
ABSTRACT
To study bioadhesive property of carbomer 934 in dog alimentary tract, carbomer 934 and ethylcellulose were radiolabelled with technetium-99 m. The gastrointestinal emptying rate of these materials was measured by the technique of gamma scintiscan. The results showed that the empty rate of adhesive material (carbomer 934) was remarkably slower in dog alimentary tract compared to nonadhesive material (ethylcellulose). It is concluded that, in dog, the interaction between gastrointestinal mucus layer and adhesive material or nonadhesive material was significantly different. Carbomer 934 had stronger bioadhesive property in vivo than that of ethylcellulose.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acrylic Resins
/
Diagnostic Imaging
/
Pharmacokinetics
/
Gamma Cameras
/
Cellulose
/
Radioimmunodetection
/
Digestive System
/
Gastric Emptying
/
Intestinal Mucosa
/
Metabolism
Type of study:
Diagnostic study
Limits:
Animals
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2002
Type:
Article
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