Progress in researches on sperm antigen fertilin beta

Jun ZHANG; Yanfeng LI

Progress in researches on sperm antigen fertilin beta / 中华男科学杂志

Jun ZHANG; Yanfeng LI.

National Journal of Andrology ; (12): 52-58, 2004.

Article in Chinese | WPRIM | ID: wpr-357083

ABSTRACT

ABSTRACT

Fertilin beta plays an important role in fertilization by its disintegrin domain as a sperm-specific antigen. This paper reviews its structure, localization and roles in fertilization, and suggests that fertilin beta, as an important target antigen, has a very promising value in the development of human immunocontraceptive vaccine.

Subject(s)

Animals; Humans; Male; ADAM Proteins; Contraception, Immunologic; Fertilins; Fertilization; Membrane Glycoproteins; Chemistry; Genetics; Physiology; Metalloendopeptidases; Chemistry; Genetics; Physiology; Vaccines; Allergy and Immunology

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Membrane Glycoproteins / Metalloendopeptidases / Vaccines / Chemistry / Contraception, Immunologic / Allergy and Immunology / ADAM Proteins / Fertilization / Fertilins Limits: Animals / Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2004 Type: Article

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