A study of aspermia-related genes by genchips and analysis of the RAP1A gene / 中华男科学杂志
National Journal of Andrology
;
(12): 654-657, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-357117
ABSTRACT
<p><b>OBJECTIVE</b>To study the differential gene expression profiles between the normal and aspermia human testes by genechips.</p><p><b>METHODS</b>Probes were prepared from mRNA extracted from both normal and aspermia testes and employed on Biostar H-40s genechips to detect the differential gene expression profiles. A distinctly up-regulated gene RAP1A was analyzed by bibliogrphic retrieval.</p><p><b>RESULTS</b>Six hundred and twenty-three differential expressed genes were found, among which the distinctly up-regulated gene RAP1A was closely related to human sperm regulation.</p><p><b>CONCLUSIONS</b>Screening the differential gene expression profiles between the normal and aspermia human testes by genechips can be used in the study of aspermia-related genes.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oligospermia
/
Oligonucleotide Array Sequence Analysis
/
Rap1 GTP-Binding Proteins
/
Gene Expression Profiling
/
Genetics
/
Methods
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2003
Type:
Article
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