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Analysis of the Physiological Activities and Functions in Vitro of Apheresis Platelets during Storage / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 856-860, 2015.
Article in Chinese | WPRIM | ID: wpr-357258
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the changes of physiological activities and functions in vitro of apheresis platelets during storage.</p><p><b>METHOD</b>17 units of apheresis platelets were randomly chosen and stored at 20 °C to 24 °C with agitation. Platelet counting (Plt), mean platelet volume (MPV), blood gases, pH value, glucose (Glu) concentration, lactate (LA) concentration, LDH concentration, thromboelastogram (TEG), hypotonic shock response (HSR), CD62p expression rate and anew expression rate were measured on days 0, 1, 3, 5 after platelet storage. Changes of physiological activities and functions in vitro were systematically evaluated by above-mentioned indexes.</p><p><b>RESULTS</b>During storage, Plt, MPV and HSR were not significantly changed; but pH value, blood gases, Glu, LA, LDH, HSR, expression rate of CD62p and anew expression rate were significant differenty. Among thromboelastogram indexes, R value increased obviously with prolongation of storage time; K value and αAngle were not significantly changed; MA was not significantly changed on day 1 and 3, but was slightly increase on day 5.</p><p><b>CONCLUSION</b>The physiological activities and functions in vitro of apheresis platelets are kept well during storage. For clinical transfusion of apheresis platelet during storage, clinical effect of transfusione is not influenced.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Platelet Count / Thrombelastography / Blood Platelets / Blood Preservation / In Vitro Techniques / Plateletpheresis Limits: Humans Language: Chinese Journal: Journal of Experimental Hematology Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Platelet Count / Thrombelastography / Blood Platelets / Blood Preservation / In Vitro Techniques / Plateletpheresis Limits: Humans Language: Chinese Journal: Journal of Experimental Hematology Year: 2015 Type: Article