Synthesis and properties of poly(hydroxyethyl methacrylate) hydrogel for IOL materials / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 595-598, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-357644
ABSTRACT
Poly (hydroxyethyl methacrylate) (PHEMA) hydrogel for intraocular lens (IOL) materials was synthesized by solution polymerization using 2-hydroxyethyl methacrylate (HEMA) as raw material, ammonium persulfate and sodium pyrosulfite (KPS/SMBS) as catalyst, and trietyleneglycole dimethacrylate (TEGDMA) as cross-linking additive. Effects of reaction time, temperature, dosage of catalyst and cross-linking additive on mechanical strength and the equilibrium water content (EWC) of the PHEMA hydrogel were systematically investigated and their structure and optical property were also characterized. The experimental results showed that the optimum conditions for preparing PHEMA hydrogel are catalyst 0.5 wt%, cross-linking additive 1.0 wt%, reaction temperature 40 degrees C, reaction time 36 h. Under the optimum conditions, the tensile strength of PHEMA hydrogel prepared is as high as 0.57 MPa, hardness of Shore A is 23.0, EWC is over 40%, and light transmittance is over 97%.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyhydroxyethyl Methacrylate
/
Tensile Strength
/
Biocompatible Materials
/
Chemistry
/
Hydrogel, Polyethylene Glycol Dimethacrylate
/
Lenses, Intraocular
Limits:
Humans
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2007
Type:
Article
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