A Case of Lupus Erythematosus Panniculitis with Infiltration of Atypical Lymphocytes / 대한피부과학회지
Korean Journal of Dermatology
;
: 1074-1077, 1998.
Article
in Korean
| WPRIM
| ID: wpr-35778
ABSTRACT
Lupus erythematosus panniculitis is a rare variant of lupus erythematosus primarily involving a panniculus with or without discoid lupus erythematosus in the overlying skin. A 34-year-old woman showed multiple, variable-sized, indurated subcutaneous nodules on both her upper arms and axillae. A Histopathological examination revealed lobular panniculitis with infiltration of several hyperchromatic atypical large lymphocytes. The infiltrated cells were positively stained with LCA, UCHL-1, CD4, CD8, but not with CD20 and CD68. A T cell receptor -chain gene and immunoglobulin heavy chain gene rearrangement study showed no monoclonality. The result of an ANA test was positive at 1 40 in a homogeneous pattern. Skin lesions were improved by combined therapy with daily hydroxychloroquine 400mg and prednisolone 10mg in a week and after 6weeks, resolved with atrophic depressed scars. After 4 months, she complained of symptoms of the Raynaud phenomenon and was managed by nifedipine. There has been no recurrence during follow-up for 7 months.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arm
/
Raynaud Disease
/
Recurrence
/
Skin
/
Axilla
/
Lupus Erythematosus, Discoid
/
Prednisolone
/
Lymphocytes
/
Nifedipine
/
Receptors, Antigen, T-Cell
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1998
Type:
Article
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