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Effect of Zinc Doped Calcium Phosphate Coating on Bone Formation and the Underlying Biological Mechanism / 生物医学工程学杂志
Journal of Biomedical Engineering ; (6): 1359-1363, 2015.
Article in Chinese | WPRIM | ID: wpr-357867
ABSTRACT
Implant surface modified coating can improve its osteoinductivity, about which simple calcium phosphate coating has been extensively studied. But it has slow osteointegration speed and poor antibacterial property, while other metal ions added, such as nano zinc ion, can compensate for these deficiencies. This paper describes the incorporation form, the effect on physical and chemical properties of the material and the antibacterial property of nano zinc, and summarizes the material's biological property given by calcium ion, zinc ion and inorganic phosphate (Pi), mainly focusing on the influence of these three inorganic ions on osteoblast proliferation, differentiation, protein synthesis and matrix mineralization in order to present the positive function of zinc doped calcium phosphate in the field of bone formation.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoblasts / Osteogenesis / Phosphates / Zinc / Biocompatible Materials / Calcium Phosphates / Cell Differentiation / Chemistry / Calcium / Cell Biology Limits: Humans Language: Chinese Journal: Journal of Biomedical Engineering Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoblasts / Osteogenesis / Phosphates / Zinc / Biocompatible Materials / Calcium Phosphates / Cell Differentiation / Chemistry / Calcium / Cell Biology Limits: Humans Language: Chinese Journal: Journal of Biomedical Engineering Year: 2015 Type: Article