Molecular regulatory mechanism of tooth root development / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 177-181, 2012.
Article
in English
| WPRIM
| ID: wpr-358211
ABSTRACT
The root is crucial for the physiological function of the tooth, and a healthy root allows an artificial crown to function as required clinically. Tooth crown development has been studied intensively during the last few decades, but root development remains not well understood. Here we review the root development processes, including cell fate determination, induction of odontoblast and cementoblast differentiation, interaction of root epithelium and mesenchyme, and other molecular mechanisms. This review summarizes our current understanding of the signaling cascades and mechanisms involved in root development. It also sets the stage for de novo tooth regeneration.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Tooth Root
/
Signal Transduction
/
Cell Differentiation
/
Embryology
/
Dental Cementum
/
Epithelium
/
Genetics
/
Mesoderm
/
Molecular Biology
Limits:
Humans
Language:
English
Journal:
International Journal of Oral Science
Year:
2012
Type:
Article
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