Clinical analysis of 15 patients with pulmonary malignant fibrous histiocytoma / 中国肺癌杂志

ABSTRACT

<p><b>BACKGROUND</b>Pulmonary malignant fibrous histiocytoma (MFH) is very rare and it is worthy to study the clinical characteristics, treatment method and prognosis of primary pulmonary MFH.</p><p><b>METHODS</b>Fifteen patients with primary pulmonary MFH were reviewed retrospectively.</p><p><b>RESULTS</b>There were 10 males and 5 females. Their ages were 56.2 years±14.0 years (20-72 years). MFH mainly manifested as cough, hemoptysis, fever, chest pain and breathlessness. The diameters of tumors were 8.3 cm±8.0 cm, ranged from 0.3 to 35 cm. All the patients received surgical operations, including 5 pneumonect-omy, 8 lobectomy and 2 exploration. The overall 1-, 3-and 5-year survival rate of 15 patients was 56.2%, 24.1% and 16.7% respectively. Incomplete surgical excision of tumor significantly influenced survival.</p><p><b>CONCLUSIONS</b>Pulmonary MFH is a high-grade malignant tumor with poor prognosis, and surgery is the main treatment method.</p>