Microgravity-induced cardiovascular deconditioning: mechanisms and countermeasures / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 532-539, 2012.
Article
in English
| WPRIM
| ID: wpr-358702
ABSTRACT
It has been demonstrated that individuals exposed to actual or simulated microgravity often experience cardiovascular dysfunctions when returning to Earth. The underlying mechanisms of orthostatic intolerance and countermeasure treatment are still poorly understood. In this paper, the progress in the mechanism of cardiovascular deconditioning from the view of vascular remodeling, increased venous compliance in the lower limbs, cellular proliferation and differentiation, and cell signaling pathway was reviewed. Meanwhile, an overview of the countermeasures including exercise, lower body negative pressure, thigh cuffs, traditional Chinese herb medicine and artificial gravity was presented.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Weightlessness
/
Cell Communication
/
Cell Differentiation
/
Weightlessness Simulation
/
Gravity, Altered
/
Cardiovascular Deconditioning
/
Cell Proliferation
/
Vascular Remodeling
Limits:
Humans
Language:
English
Journal:
Chinese Journal of Applied Physiology
Year:
2012
Type:
Article
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