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Efficacy and Safety of Intravenous Propofol Anesthesia during Transrectal Ultrasound-Guided Prostate Biopsy
Korean Journal of Urology ; : 757-761, 2009.
Article in Korean | WPRIM | ID: wpr-35895
ABSTRACT

PURPOSE:

Transrectal ultrasonography (TRUS)-guided prostate biopsy causes fear and pain in 65% to 90% of patients. This study was designed to evaluated the use of intravenous propofol anesthesia during TRUS-guided prostate biopsy. MATERIALS AND

METHODS:

Between January 2006 and June 2008, 195 men undergoing a transrectal prostate biopsy were divided into 2 groups according to anesthetic technique. Group A consisted of 99 patients who received intravenous propofol infusion through an 18 gauge needle during TRUS-guided prostate biopsy. Group B consisted of 96 patients who intrarectally received 10 ml of 2% lidocaine gel 10 minutes before TRUS-guided prostate biopsy. Pain scores were assessed on a visual analogue scale immediately after prostate biopsy.

RESULTS:

The pain score was significantly reduced in group A compared with group B. There was a significant difference in the mean pain score between the 2 groups (1.0+/-1.3 in group A versus 2.9+/-2.0 in group B; p<0.01). Also, there was a significant difference in the willingness to undergo rebiopsy between the 2 groups (83.8% in group A versus 17.7% in group B; p<0.01). However, the complication rates were not significantly different between the 2 groups. Gross hematuria was found in 14% of group A patients and 18% of group B patients.

CONCLUSIONS:

Our results proved the advantage of intravenous propofol anesthesia during TRUS-guided prostate biopsy. Intravenous propofol infusion can be a safe and simple technique that significantly reduces pain during TRUS-guided prostate biopsy.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Prostate / Biopsy / Propofol / Hematuria / Imidazoles / Anesthesia / Lidocaine / Needles / Nitro Compounds Limits: Humans / Male Language: Korean Journal: Korean Journal of Urology Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prostate / Biopsy / Propofol / Hematuria / Imidazoles / Anesthesia / Lidocaine / Needles / Nitro Compounds Limits: Humans / Male Language: Korean Journal: Korean Journal of Urology Year: 2009 Type: Article