In Situ Polymerization and Characterization of Hydroxyapatite/polyurethane Implanted Material / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 826-831, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-359561
ABSTRACT
In order to improve the interfacial bonding strength of hydroxyapatite/polyurethane implanted material and dispersion of hydroxyapatite in the polyurethane matrix, we in the present study synthesized nano-hydroxyapatite/polyurethane composites by in situ polymerization. We then characterized and analyzed the fracture morphology, thermal stability, glass transition temperature and mechanical properties. We seeded MG63 cells on composites to evaluate the cytocompatibility of the composites. In situ polymerization could improve the interfacial bonding strength, ameliorate dispersion of hydroxyapatite in the properties of the composites. After adding 20 wt% hydroxyapatite into the polyurethane, the thermal stability was improved and the glass transition temperatures were increased. The tensile strength and maximum elongation were 6.83 MPa and 861.17%, respectively. Compared with those of pure polyurethane the tensile strength and maximum elongation increased by 236.45% and 143.30%, respectively. The composites were helpful for cell adhesion and proliferation in cultivation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyurethanes
/
Tensile Strength
/
Biocompatible Materials
/
Cell Adhesion
/
Cell Line
/
Chemistry
/
Durapatite
/
Transition Temperature
/
Polymerization
Limits:
Humans
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2015
Type:
Article
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