Determination of reference concentrations of strontium in urine by inductively coupled plasma atomic emission spectrometry
Environmental Health and Preventive Medicine
;
: 11-16, 2006.
Article
in English
| WPRIM
| ID: wpr-359906
ABSTRACT
<p><b>OBJECTIVE</b>The aim of this study was to establish reference concentrations of urinary strontium by inductively coupled plasma atomic emission spectrometry (ICP-AES).</p><p><b>METHODS</b>For the determination of strontium, urine samples were collected from healthy Japanese (n=146; 115 males, 31 females; mean age, 33±9 years; age range, 18 to 58 years). The urine samples stored at or below -20°C were thawed with incubation at 40°C for 30 min and sediments were dissolved by vigorous shakings. Then, the samples were centrifuged at 3000 g for 5 min, and the supernatant was directly aspired into a P-5200-3600/1200 ICP-AES system from Hitachi Ltd., Tokyo, Japan.</p><p><b>RESULTS</b>A steeper increase in the S/N ratio and a good effective linearity of the calibration line was obtained at 407.771 nm in the range of 0-300 μg/L strontium standard solution. Urine samples having the same background signal as that of 18 MΩ cm ultrapure blank water, a good correspondence of the single peak pattern of the spectra, accuracy and precision of spike recovery were also confirmed. Urinary strontium concentrations showed a log-normal distribution and a geometric mean concentration of 143.9 μg/L, with 5-95% confidential interval of 40.9-505.8 μg/L.</p><p><b>CONCLUSION</b>The results of this study will be useful as guidelines for the biological monitoring of strontium in normal subjects and in individuals therapeutically or environmentally exposed to strontium.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
Language:
English
Journal:
Environmental Health and Preventive Medicine
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS