Effects of 17beta-estradiol on distribution of primordial germ cell migration in male chicks / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 243-248, 2008.
Article
in English
| WPRIM
| ID: wpr-359962
ABSTRACT
<p><b>AIM</b>To assess whether exogenous estradiol has any effect on migration of primordial germ cells (PGCs) in the chick.</p><p><b>METHODS</b>Fertilized eggs were treated with 17beta-estradiol (E(2)) (80 microg/egg) at stage X (day 0 of incubation), stages 8-10 (incubation 30 h) and 13-15 (incubation 55 h). Controls received vehicle (emulsion) only. Changes in PGC number were measured on different days according to developmental stages.</p><p><b>RESULTS</b>In male right gonads, but not in female left gonads, at stages 28-30 (incubation 132 h) significant decreases in the mean number of PGCs aggregating were observed compared with the controls (P < 0.05) while the total PGC number in the right and left gonads at each stage did not change (P > 0.05).</p><p><b>CONCLUSION</b>The present study provides evidence that E(2) has significant effects on the localization of PGCs in male right, but not female left, gonads of chicken embryos at stages 28-30, compared with controls.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Cell Movement
/
Estradiol
/
Germ Cells
/
Gonads
Limits:
Animals
Language:
English
Journal:
Asian Journal of Andrology
Year:
2008
Type:
Article
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