Association between gingival crevicular fluid leptin level and periodontal parameters in patients with aggressive periodontitis / 中华口腔医学杂志
Chinese Journal of Stomatology
; (12): 733-736, 2014.
Article
in Zh
| WPRIM
| ID: wpr-360489
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To determine the level of leptin in gingival crevicular fluid (GCF) of patients with aggressive periodontitis (AgP) and to analyze the relationship between leptin and periodontal cilinical parameters.</p><p><b>METHODS</b>Fifty-four patients with AgP and 30 healthy controls were recruited. Detailed clinical examinations were conducted, and clinical parameters such as bleeding index (BI), probing depth (PD), attachment loss (AL) were recorded. Two teeth were selected as test teeth in each subject, one from posterior area and the other from anterior region. The level of GCF leptin was measured by enzyme linked immunosorbent assay.</p><p><b>RESULTS</b>The level of GCF leptin in AgP patients was significantly lower than that of control subjects [(16.5±4.6) ng vs.(26.0±6.0) ng, P < 0.05]. The level of GCF leptin was negatively related to BI (-0.306, P < 0.01), PD (-0.346, P < 0.01) and AL (-0.250, P < 0.01).</p><p><b>CONCLUSIONS</b>AgP patients have significantly decreased level of GCF leptin and the level of leptin was negatively related to BI, PD and AL.</p>
Full text:
1
Index:
WPRIM
Main subject:
Aggressive Periodontitis
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Enzyme-Linked Immunosorbent Assay
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Case-Control Studies
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Chemistry
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Periodontal Index
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Gingival Crevicular Fluid
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Leptin
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Metabolism
Type of study:
Observational_studies
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Risk_factors_studies
Limits:
Adult
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Stomatology
Year:
2014
Type:
Article