An Autopsy Case of Amyotrophic Lateral Sclerosis with Neuroinflammatory change
Journal of the Korean Neurological Association
;
: 128-131, 2012.
Article
in Korean
| WPRIM
| ID: wpr-36049
ABSTRACT
Neuroinflammation such as reactive gliosis and microglial activations are important pathological findings of ALS. We present a first autopsy case of ALS in Korea related with neuroinflammatory change. A 67-year-old ALS patient suddenly expired due to accidental head trauma. Gross autopsy finding showed marked atrophic change in spinal cord. Pathological finding include a marked loss of motor neurons, reactive gliosis and microglial infiltrations. These findings suggest neuroinflammation may play a role in pathogenesis of ALS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spinal Cord
/
Autopsy
/
Gliosis
/
Craniocerebral Trauma
/
Amyotrophic Lateral Sclerosis
/
Korea
/
Motor Neurons
Limits:
Aged
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
2012
Type:
Article
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