Effects of electromagnetic pulse on bone metabolism of mice in vivo / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 518-521, 2009.
Article
in English
| WPRIM
| ID: wpr-360633
ABSTRACT
<p><b>OBJECTIVE</b>To study the effects of electromagnetic pulse (EMP) on bone metabolism of mice in vivo.</p><p><b>METHODS</b>Twenty-four male BALB/c mice were divided into a control group and 2 experimental groups (n=8). The whole-body of mice in experimental groups were exposed to 50 kV/m and 400kV/m EMP, 400 pulses daily for 7 consecutive days at 2 seconds intervals. Alkaline phosphotase (ALP) activity, serum calcium concentration and osteocalcin level and trabecular bone volume (BV/TV, %) were measured immediately after EMP exposure by biochemical, ELISA and morphological methods.</p><p><b>RESULTS</b>The ALP activity, serum calcium concentration and osteocalcin level and BV/TV in experimental groups remained unchanged after EMP exposure. Conclusion Under our experimental conditions, EMP exposure cannot affect bone metabolism of mice in vivo.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Bone and Bones
/
Osteocalcin
/
Electromagnetic Fields
/
Alkaline Phosphatase
/
Metabolism
/
Mice, Inbred BALB C
Limits:
Animals
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2009
Type:
Article
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