Acute Caffeine Effect on Repeatedly Measured P300
Environmental Health and Preventive Medicine
;
: 13-17, 2000.
Article
in Japanese
| WPRIM
| ID: wpr-361589
ABSTRACT
The acute effect of a single−dose of caffeine on the P300 event−related brain potential (ERP) was assessed in a study using a repeatedly presented auditory oddball button−press task. A dose (5mg/kg body−weight) of either caffeine or placebo lactose, dissolved in a cup of decaffeinated coffee, was administered double−blindly to coffee drinkers who had abstained from coffee for 24hrs, with the presentation order of the sessions counterbalanced and separated by 2−4 weeks. The caffeine−treatment condition demonstrated a smaller P300 amplitude and a shorter latency overall than the placebo treatment condition. The mean P300 amplitude value difference (caffeine minus placebo) increased with the successive trial blocks. Caffeine ingestion appears to yield a lower resource−consumption and a net increase in allocating attention resources for task performance across repeated measurements.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Placebos
/
Caffeine
Type of study:
Controlled clinical trial
Language:
Japanese
Journal:
Environmental Health and Preventive Medicine
Year:
2000
Type:
Article
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