The Effect of Low-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Unilateral Spatial Neglect and Changes in Regional Cerebral Blood Flow (rCBF) / The Japanese Journal of Rehabilitation Medicine
The Japanese Journal of Rehabilitation Medicine
;
: 542-553, 2007.
Article
in Japanese
| WPRIM
| ID: wpr-362162
ABSTRACT
Objective:
To describe the effect of low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) on unilateral spatial neglect (USN) in 22 right-handed stroke patients with right hemispheric damage and the corresponding change of regional cerebral blood flow (rCBF) before and after rTMS, speculating on the neural basis for recovery from USN.Methods:
The time of onset to the initiation of rTMS was 70 to 220 days (mean 128.3 days), on chronic stage in all patients. The therapeutic schedule consisted of 7 sessions of 1 Hz-rTMS delivered every other day for two weeks, with 14 sessions in two patients. Each session consisted of one train of 500 pulses applied over P5 (10/20 EEG system) at 90% motor threshold using a figure-eight-shaped coil. Assessment was made using the Japanese edition of the Behavioural Inattention Test (BIT) and a computed visual search task at four times as well as a cold-xenon CT (Xe-CT) at two times.Results:
rTMS induced a significant improvement of USN patient performance in cancellation tasks and the BIT figure copy task as well as in visual search reaction time, an improvement which lasted 2 weeks after rTMS. Xe-CT showed a significant increase in rCBF in the right cerebellum after rTMS.Conclusions:
It is conceivable that low-frequency rTMS may be useful for improving USN and it is a promising therapeutic tool. Also, the cerebellum, by forming a neural network with the parietal and frontal lobe, may play an important role in patient recovery from spatial neglect.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Japanese
Journal:
The Japanese Journal of Rehabilitation Medicine
Year:
2007
Type:
Article
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