Clinical Characteristics of Nosocomial Infective Endocarditis in a Tertiary Referral Hospital
Korean Circulation Journal
;
: 236-241, 2006.
Article
in Korean
| WPRIM
| ID: wpr-36298
ABSTRACT
BACKGROUND AND OBJECTIVES:
Despite case reports of nosocomial infective endocarditis (NIE), the clinical characteristics of the hospital acquired infective endocarditis have not been investigated in Korea. SUBJECTS ANDMETHODS:
The clinical records of patients with infective endocarditis, treated at Asan Medical Center between January 1989 and December 2003, were retrospectively analyzed.RESULTS:
Of the 309 case of native-valve endocarditis, 17 (5.5%) cases were found to be NIE. The mean age of these 17 patients was 51+/-17 years, which included 9 women and 8 men. Staphylococcus aureus was the most frequent causative organism of NIE in 11 cases (65%), of which nine (82%) had methicillin-resistant strains. The prevalence of right-sided vegetation in NIE was higher than that of community acquired infective endocarditis (CIE)(29 vs. 10%, p<0.05); however, left-sided vegetation was observed in more than 70% of patients with NIE (12/17). Surgeries, with or without wound infection (59%) and insertion of a central venous catheter (29%), were the two most common possible sources of NIE. In hospital mortality was significantly higher in patients with NIE than in those with CIE (47 vs. 11%, p<0.001).CONCLUSION:
Patients with NIE, which comprises a minor portion of those with infective endocarditis, show unique clinical characteristics in terms of causative organisms, risk factors, sites of vegetation and in-hospital mortality.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Staphylococcus aureus
/
Wound Infection
/
Cross Infection
/
Prevalence
/
Retrospective Studies
/
Risk Factors
/
Methicillin Resistance
/
Hospital Mortality
/
Endocarditis
/
Central Venous Catheters
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Circulation Journal
Year:
2006
Type:
Article
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