Decreased bone mineral density is associated with coronary atherosclerosis in healthy postmenopausal women
Obstetrics & Gynecology Science
;
: 144-149, 2015.
Article
in English
| WPRIM
| ID: wpr-36572
ABSTRACT
OBJECTIVE:
This study aimed to assess the association between bone mineral density (BMD) and coronary atherosclerosis in healthy postmenopausal women.METHODS:
We performed a retrospective review of 252 postmenopausal women who had visited a health promotion center for a routine checkup. BMD of the lumbar spine (L1-L4) and femoral neck was evaluated using dual-energy X-ray absorptiometry, and coronary atherosclerosis was assessed using 64-row multidetector computed tomography. Participants were divided into normal BMD and osteopenia-osteoporosis groups, according to the T-scores of their lumbar spine or femoral neck.RESULTS:
Participants with osteopenia-osteoporosis had a significantly higher proportion of coronary atherosclerosis than did those with normal BMD at the lumbar spine (P=0.003) and femoral neck (P=0.004). Osteopenia-osteoporosis at the lumbar spine (odds ratio [OR], 2.86; 95% confidence interval [CI], 1.12 to 7.27) or femoral neck (OR, 3.35; 95% CI, 1.07 to 10.57) was associated with coronary atherosclerosis, after controlling for age and cardiovascular risk factors.CONCLUSION:
Decreased BMD is associated with coronary atherosclerosis in healthy postmenopausal women, independent of age and cardiovascular risk factors. Postmenopausal women with decreased BMD may have a higher risk of developing coronary atherosclerosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spine
/
Coronary Artery Disease
/
Menopause
/
Absorptiometry, Photon
/
Bone Density
/
Retrospective Studies
/
Risk Factors
/
Femur Neck
/
Multidetector Computed Tomography
/
Health Promotion
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Female
/
Humans
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2015
Type:
Article
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