Renal Function and Hemolysis Associated with Intraoperative Autotransfusion in Abdominal Aortic Surgery / 日本心臓血管外科学会雑誌

ABSTRACT

Renal function, hemolysis and hematologic parameters after transfusion using a cell-separation (CS) device were retrospectively evaluated during abdominal aortic aneurysm repair. Fifty-eight patients were divided into two groups, that is, the CS group (<i>n</i>=39) who received autologous retransfusion using the CS device and the non-CS group (<i>n</i>=19) who were operated before 1989, when we started to use CS device in our operating theater. Hematologic parameters and levels of GOT, GPT, LDH, BUN and creatinine were assessed before and 1, 2, 3, 4 and 7 days after the operation. Mean transfused homologous blood was 1.3±1.8 units in the CS groups and 4.9±3.1 units in the non-CS group (<i>p</i><0.05). Peak levels of LDH and GPT were significantly higher in the CS group than the non-CS group (<i>p</i><0.05) after the operation (GOT, CS group 60.4±29.1IU/<i>l</i> vs non-CS group 34.8±12.3IU/<i>l</i>, LDH, CS group 643±324IU/<i>l</i> vs non-CS group 446±108IU/l). There was no significant difference in the levels of BUN and creatinine levels between the two groups. Hemoglobin levels decreased gradually after the operation in CS group patients who did not receive a homologous blood transfusion. These data suggested that mild hemolysis occurred after retransfusion of autologous blood, but that the hemolysis due to the CS device had no effect on the renal function of the patients.