Suppressive Effects of Kambaku-taiso-to on the Yawning Induced by Dopaminergic Agonist in Rats / 日本東洋医学雑誌
Kampo Medicine
;
: 53-57, 1997.
Article
in Japanese
| WPRIM
| ID: wpr-368217
ABSTRACT
The present experiments were performed to investigate the potential role of Kambaku taiso-to (Gan mai da zao tang) in modifying the occurrence of yawning in rats. Subcutaneous injection of talipexole, a selective dopamine D-2 receptor agonist, at 5-100μg/kg, elicits yawning behavior for over one hour, the maximal effect being observed at a dose of 25μg/kg. Kambaku-taiso-to significantly suppressed the incidence of yawning induced by talipexole. These results suggest that Kambaku-taiso-to exerts a suppressive effect on the incidence of yawning.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Japanese
Journal:
Kampo Medicine
Year:
1997
Type:
Article
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