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Hematological Change in the Adjuvant-Induced Arthritis of Rats (II). Effects of Kampo Medicine Extracts on the Inflammatory Index Substances and Platelet / 日本東洋医学雑誌
Kampo Medicine ; : 597-605, 1999.
Article in Japanese | WPRIM | ID: wpr-368271
ABSTRACT
The hematological effects of Sokeikakketsu-to, Yokuinin-to, Keisi-ka-jutsubsu-to, Eppi-ka-jutsu-to, and Sairei-to observed on the AA rats were investigated. The time course of blood count and albumin, sialic acid and acid-soluble glycoprotein in the serum whs. were measured. Sokeikakketsu-to had the strongest anti-inflammatory effect on the improvement of Inflammatory Index Substances, platelets, and the Arthritis Score for changes in synovitis. Yokuinin-to was also effective. When these Kampo medicines were administered in the early stages of AA, Sokeikakketsu-to improved the AA signficantly. The results may suggest that Sokeikakketsu-to works for the control of autoimmunity. On the other hand, Keisi-ka-jutsubu-to aggravated the AA when it was administered in the early stages of the AA.

Full text: Available Index: WPRIM (Western Pacific) Language: Japanese Journal: Kampo Medicine Year: 1999 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Japanese Journal: Kampo Medicine Year: 1999 Type: Article