Remission in a Patient with Crohn's Disease Treated by Sairei-to and Perilla Oil / 日本東洋医学雑誌

ABSTRACT

A 61-year-old female had suffered from diarrhea, abdominal pain and vomiting since 1984. Although she had been treated with anticholinergics, antidiarrhoics, and Lactobacillus derivatives, the symptoms were unchanged. In July 1988, a partial resection of the distal ileum was performed to overcome adhesive ileus, but soft or mucous feces remained after surgery. The pathological diagnosis of the specimen was Crohn's disease. From July 1994, oral administration of Sairei-to (9g/day) was started. Within two weeks, the feces became normal. The patient gained 2kg of weight in 2 months. In May 1996, the dose of Sairei-to was reduced to 6g/day without changing her condition. In September, she started to take 30g of Perilla oil every day. Sairei-to was discontinued in May 1997 after the dose was reduced to 3g/day for a month. The total duration of Sairei-to therapy was 2 years and 10 months. Ordinary defecation has been observed for 1 year and 3 months since Sairei-to was discontinued. In conclusion, a remission was achieved in a patient suffering from Crohn's disease with a long-term administration of Sairei-to, and the prescription was discontinued for more than a year without recurrence.