The Potential Effect of Ubai-en on Protein-losing Enteropathy / 日本東洋医学雑誌

ABSTRACT

A 64-year-old female who had suffered from rheumatoid arthritis (RA) for many years was admitted to our hospital because of acute abdominal pain and diarrhea. She was diagnosed with RA, Sjögren syndrome and protein-losing enteropathy (PLE) with GI tract amyloidosis. She was treated with total parenteral nutrition, prednisolone, tranexamic acid and a variety of Kampo medicines, for example kanzo-syashin-to, keishi-kashakuyaku-shoukyou-ninjin-to, and bushi-kobei-to. However, diarrhea continued and paralytic ileus occurred. Then she was treated with Ubai-en, which is known as an anti-ascarid drug or anti-diarrheic drug. Ubai-en was effective on her diarrhea in 2 weeks. This suggests that Ubai-en may be an effective treatment for PLE.