Effects of Moxibustion and Goshazinkigan for Spontaneous Fatty II Diabetes Rat / 日本東洋医学雑誌

ABSTRACT

In order to examine the effectiveness of moxibustion and Goshajinkigan for diabetes we investigated using Otsuka Long-Evans Tokushima Fatty (OLETF) rats and Long-Evans Tokushima Otsuka (LETO) rats. 18 male OLETF rats (5 weeks old) and 6 male LETO rats (5 weeks old) were divided into 4 groups. Group I rats were given trial moxibustion (BL 20, BL 23). Group II rats were administered Goshajinkigan (100mg/kg). Group III (OLETF) and IV (OLETF) rats were untreated as controls. In each group, we measured body weight (BW), blood sugar (BS), urine albumin (UA), pain-related time (PRT) and blood flow volume (BFV) before and after the experiment. Moreover, kidney and pancreas tissues were observed.<br>In groups I, II and III, BW, BS and UA increased in comparison with that of group IV, as the rats grew older. But groups I and II showed suppressed increases, in comparison with that of III group. After stimulation groups I and II showed reaction sensitivity, in comparison with group III. Group I showed a suppressed decrease of BFV. Tissue samples showed no serious change.<br>These findings suggest that moxibustion and Goshajinkigan inhibited some quantity of the progress of diabetic disease.