Study on the cells in the cerebro-spinal fluid by CYTOSPIN technique in 107 patients in the Ho Chi Minh center for Hematology and Blood Transfusion

ABSTRACT

Study on 107 cases from Jan 1999 to Aug 1999, their results are found as follows - All in adults 25 cases (23.36%). Male - female ratio 1.08 - all in children (treated to Fralle 93) 70 cases (65.43%). Male- female ratio 1.7. All in the number of WBC > 50 x 109/l 2 cases (1.87%). AML type M4 1 case (0.93%). -AML type M5 2 cases (1.87%). CML transformed to ALL 1 case (0.93%). Lymphoma 4 cases (3.74%), 100% male.- Patient with meningeal syndrome 2 cases (1.78%). From the above results, we have some conclusions as follows * The types of high meningeal recurrence are -Early meningeal recurrence 85.71% - Simple meningeal recurrence 85.71% - Patients incompletely cured to standard protocol 64.29%. *The incidence of the central nervous damage caused by ALL in children (20%) is higher than adults (12%). * As to ALL in children, the incidence of meningeal recurrence increases depending on risk group group C>group B> group A. *Children completely cured to the standard protocol (Fralle93) has a substantially decreased menigeal recurrence (29%, decreased for group B, and 34% decreased for group C).