Effect of physical training on the metabolism of serum and arterial cholesterol / 体力科学
Japanese Journal of Physical Fitness and Sports Medicine
;
: 95-102, 1987.
Article
in Japanese
| WPRIM
| ID: wpr-371409
ABSTRACT
The effect of a treadmill running program on the metabolism of cholesterol in serum and in arterial wall was studied in male Wistar rats, aged 7 weeks and weighing about 200 g- Rats were exercised on 6 days a week for 8 week, running 1, 000 m a day at 15 m/min. The trained rats gave the follwing evidence, as compared with the sedentary control animals<BR>1. Remarkably lower body weight<BR>2. Significantly lower level of serum cholesterol-total, free, and LDL cholesterol<BR>3. Elevated in vivo incorporation of <SUP>14</SUP>C-mevalonate into serum cholesterol<BR>4. Enhancement of lecithin-cholesterol acyltransferase activity in serum<BR>5. Decrease in the amount of cholesterol in arterial wall cells<BR>6. Increase in in vivo incorporation of <SUP>14</SUP>C-mevalonate into arterial cholesterol.<BR>The results indicate that the excersice promotes the turnover of cholesterol in serum and arterial wall, repressing the accumulation of choleterol ester in arterial wall cells, and a prophylactic effect of the physical training for arteriosclerotic diseases has been suggested.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Japanese
Journal:
Japanese Journal of Physical Fitness and Sports Medicine
Year:
1987
Type:
Article
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