Inefficacy of residual sodium succinate on tissue perfusion with an artificial CO2 bath / 日本温泉気候物理医学会雑誌

ABSTRACT

Sodium succinate is remained behind following artificial CO₂ bathing, prepared with a 50g sodium hydrogencarbonate and succinic acid tablet producing fine bubbles in water.<br>2NaHCO₂+(CH₂)₂→(COOH)₂→(CH₂)₂(COONa)₂+H₂O+CO₂<br>Na₂CO₃+(CH₂)₂(COOH)₂→(CH₂)₂(COONa)₂+H₂O+CO₂<br>Balneotherapeutic effect of sodium succinate was evaluated experimentally using 10 rabbits by means of medical mass spectrometry.<br>Subcutaneous PO₂ and PCO₂ did not change during the bathing and tissue perfusion of 21.30±3.48ml/100g/min (mean±standard error), SD=4.94, p<0.05 was evaluated at 36-37°C, demonstrating no significant difference compared with that of 20.85±3.56ml/100g/min, SD=6.71, p<0.05 by plain water bathing.<br>These data showed clearly that the balneotherapeutic effects of an artificial CO₂ bathing prepared with a CO₂-tablet, “BUB”-KAO, was not from organic salt of sodium succinate but from CO₂.