A Case of Poisoning with Smithion Leading to Chronic Psychiatric Symptoms / 日本農村医学会雑誌

ABSTRACT

A 30-year-old male with manic-depressive psychosis took in 30ml of undiluted Smithion to commit suicide. Ten hours or so later, he was found in state of subconsciousness and admitted into our hospital.<BR>1. From the initial trance, he fell into a twilight state. After suffering from an amnestic syndrome and encountering difficulties in concentrating his attention, he was found in a depressive state on the 18th day. This depressive state was presumably a recurrence of the depression with which he had once suffered and therefore proved different from the depressive state unique to organophosphate poisoning.<BR>2. In respect to the psychatric symptoms caused by acute and subacute organophosphate poisoning and its sequela, a study is made on the basis of literature to make some comment.<BR>3. After a clinical course of two-and-a-half years, it was found that there were a slight degree of disturbance to registration and a drop in mental capacity. These were considered sequelas. These symptoms would not hamper his everyday life, but there were signs of a rise in the sense of quilty conscience and misery when he was in a depressive state.<BR>4. EEG indicates that the waves were slowing and paroxismal or sporadic small spikes. Two years later, EEG-findings were slightly abnormal with many sporadic slow α waves. No abnormalities were observed in computerized tomogram.