Study on some factors influencing on dehydroepiandrosterone absorption potential through skin from the drug distribution system
Pharmaceutical Journal
;
: 10-12, 2005.
Article
in Vietnamese
| WPRIM
| ID: wpr-3732
ABSTRACT
The effects of the type of plasticizers and concentration of active substance on skin permeation properties of DHEA from patches were studied. The results showed that propylen glycol (as a plasticizer) could improve the skin permeation rate of DHEA significantly comparing with medium chain triglycerid. When the concentrations of DHEA in the patch increased, the skin permeation rates of DHEA increased linearly until DHEA solubility saturates in the matrix. But while the concentrations of DHEA in the patch were higher, DHEA could change in to the crystalline form that makes decreasing of the skin permeation rate of DHEA
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmaceutical Preparations
/
Dehydroepiandrosterone
Language:
Vietnamese
Journal:
Pharmaceutical Journal
Year:
2005
Type:
Article
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