Studies on oral adsorbents for treatment of paraquat intoxication / 日本農村医学会雑誌

ABSTRACT

Oral adsorbents used in the primary treatment of paraquat intoxication were studied in saline to evaluate their effectiveness in terms of removal ratio and removal rate.<BR>Forty kinds of materials were tested as paraquat adsorbents.<BR>Although cation exchange resin had the greatest removal ratio for paraquat, a high removal ratio was registered by an activated carbon derived from petroleum pitch. A significant correlation between removal ratio and the degree of crosslinkage in the resin was found.<BR>The degree of paraquat concentration decrease was high when cation exchange resin was used. A significant correlation was found between the kinetic constant, which was calculated from the equation for a first-order reaction, and the degree of crosslinkage in the resin.