Fine Needle Aspiration Cytology of Langerhans Cell Histiocytosis of Mandible: A Case Report
Korean Journal of Pathology
;
: 106-109, 2010.
Article
in English
| WPRIM
| ID: wpr-37339
ABSTRACT
We present a case of mandibular involvement with Langerhans cell histiocytosis (LCH), diagnosed by ultrasound-guided aspiration and subsequently confirmed by incisional biopsy and immunohistochemistry in an eight-year-old boy. The cytologic findings included the presence of characteristic Langerhans cells of both mononucleate and multinucleate form. Diagnostic confirmation was obtained by immunopositivity for S-100 protein and CD1a of Langerhans histiocytes on paraffin-embedded sections obtained during incisional biopsy of the right mandibular area. By reporting a case of childhood LCH, we correlate the cytologic findings with histologic features and discuss the role of aspiration cytologic diagnosis in such a rare and cytomorphologically characteristic case.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biopsy
/
Immunohistochemistry
/
S100 Proteins
/
Histiocytosis
/
Langerhans Cells
/
Histiocytosis, Langerhans-Cell
/
Biopsy, Fine-Needle
/
Histiocytes
/
Mandible
Limits:
Child
/
Humans
Language:
English
Journal:
Korean Journal of Pathology
Year:
2010
Type:
Article
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