Urinary Stones in Aomori and Metal Concentration / 日本農村医学会雑誌

ABSTRACT

A total of 950 urinary stone samples from residents in Aomori Prefecture were analyzed, and the results were examined in comparison with physiological elements in blood and urine. The concentrations of 20 metals in 310 out of the urinary stone samples were measured with the ICP emission spectrochemical analyzer and the role of each metal was analyzed.<BR>The following results were obtained.<BR>1. The frequency of calcium stones in Aomori was 83% and that of uric acid stones was 3.4%. The ratio of struvite stones was 11.4%, which was higher than the national average (7.4%).<BR>2. Serum Cr and uric acid concentrations in the uric acid stone patients were significantly high. This suggested that the renal function in the patients might deteriorate. Uric Ca and P of the calcium stone patients were significantly high.<BR>3. Metal concentrations varied wide in the same type of stones, and the metal contents in uric acid stones and cystine stones were less than those in calcium stones and struvite stones, while the concentrations of most metals in the phosphate stones were over 1.5 times as high as those in calcium oxalate stones.<BR>4. The Ca content in struvite stones ranged from a few to 30% and difference of X-ray permeation was thought to be the cause.<BR>5. The ratio metal concentration in stones and urine ranged from several hundred to several thousand, except for Mg concentration, which was as low as 80. Mg is considered to play an important role in stone formation.