Drug Use in Renal Insufficiency, Drug-induced Nephropathy / 日本農村医学会雑誌

ABSTRACT

We should decide the dose in renal insufficiency according to an attachment document, estimated by Cockroft-Gault's formula. It is better not to decide the dose only byexcretion route. In addition, we should not administer the nephrotoxic drugs, especially NSAIDs, to renal insufficiency.<BR>Also, it is necessary to pay enough attention to the overdose of drugs, which do not cause renal toxicity but cause dangerous side effects to the central nervous system.<BR>Many attachment documents have a lot of lacks in the mention for renal insufficiency and need to be improved.