A successful treatment using gabapentin against hot flashes due to LH-RH agonist in a patient with advanced prostate cancer
Palliative Care Research
;
: 334-338, 2009.
Article
in Japanese
| WPRIM
| ID: wpr-374666
ABSTRACT
<b>Purpose</b> To report a case of successful treatment using gabapentin against hot flashes due to LH-RH agonist in a patient with advanced prostate cancer. <b>Case summary</b> A male patient in his seventies with advanced prostate cancer had hot flashes due to LH-RH agonist therapy. The patient began to notice hot flashes within a few months after starting hormone treatment. Oral gabapentin was administered at a starting dose of 400mg/day and was gradually escalated to 1,200mg/day. Within 7 days of administration, the patient achieved a partial improvement of his symptoms. After 17 days of gabapentin therapy, the hot flashes significantly improved. While the patient was taking a maintenance dose of 1,200mg/day, he remained to be asymptomatic. <b>Conclusion</b> There are only a few reports (none in Japan) that show effectiveness of gabapentin against hot flashes due to hormone treatment in male patients with prostate cancer. Although the mechanism of the hot flash-relieving effect of gabapentin is not fully understood, this case report indicates that gabapentin may help treating patients suffering from intractable hot flashes. Palliat Care Res 2009; 4(2) 334-338
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Japanese
Journal:
Palliative Care Research
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS