<b>Case Cohort Study</b> / 薬剤疫学

ABSTRACT

In this article, we provide a brief summary of a case-cohort study design and an introduction of Japan Statin Study (JSS) as an example for case-cohort study conducted in Japan. In the case-cohort study, the control as a sub-cohort is randomly selected from a research cohort at the beginning of the study. As it is not necessary to be sampled a control by interesting event in the research, the study design as well as cohort study can examine some events in the same time. Therefore the study design can be also applied to pharmaco-vigilance survey. The case-cohort study design has wide application range. (Jpn J Pharmacoepidemiol 2013; 18(2) 84-89)