Effects of high phosphorous intake and jump training on the developing rat tibia / 体力科学

ABSTRACT

The extensive use of food additives has increased the phosphorous content of the modern diet, while calcium intake has remained similar to past levels according to the national standards of nutrient intake. Although exercise increase bone mineral content, the intake of phosphorus may change the exercise effect. The purpose of this study was to examine the effects of jump exercise on bone and phosphate-calcium metabolism in rats consuming high levels of dietary phosphorous. Forty-two male Wistar rats aged 8 weeks were fed either a high-phosphorus diet with a 2.0 P/Ca ratio or a normal diet with a 1.0 P/Ca ratio. Rats from each dietary group were then further assigned to undergo 8 weeks of jump exercise or to be sedentary controls. Two-way analysis of variance (ANOVA) revealed that the bone mineral content (P<0.001), strength (P<0.001), transverse thickness (P<0.001), and longitudinal thickness (P<0.001) of the tibial diaphysis were increased by jump exercise in both dietary groups. The concentrations of serum inorganic phosphorus (P<0.001), FGF23 (P<0.001), and 1-25 (OH) vitamin D (P<0.001) were increased by a high phosphorus diet, and the concentrations of serum total calcium (P<0.05) and 1-25 (OH) vitamin D (P<0.05) were increased by jump exercise in both groups. In conclusion, exercise is important to increase bone mass and bone strength in a high phosphorus intake state.